The Structure Anchoring Underfur in Outer Root Sheath Cells of Telogen Mink Hair Follicles
نویسندگان
چکیده
منابع مشابه
Expression of E6 and E7 papillomavirus oncogenes in the outer root sheath of hair follicles extends the growth phase and bypasses resting at telogen.
Hair follicle growth cycle proceeds through a series of stages in which strict control of cell proliferation, differentiation, and cell death occurs. Transgenic mice expressing human papillomavirus type 16 E6/E7 papillomavirus oncogenes in the outer root sheath (ORS) display a fur phenotype characterized by lower hair density and the ability to regenerate hair much faster than wild-type mice. R...
متن کاملDifferentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro
A specialized quiescent population of hair follicle stem cells, residing in the hair follicle outer root sheath cells (ORSCs), has previously demonstrated pluripotency for differentiation into neural stem cells (NSCs). A previous study indicated that nestin‑positive hair follicle ORSCs are able to differentiate into neurons. However, little has been reported on the isolation of nestin‑negative ...
متن کاملDesmoglein 3 anchors telogen hair in the follicle.
Little is known about the function of desmosomes in the normal structure and function of hair. Therefore, it was surprising that mice without desmoglein 3 (the autoantigen in pemphigus vulgaris) not only developed mucous membrane and skin lesions like pemphigus patients, but also developed hair loss. Analysis of this phenotype indicated that hair was normal through the first growth phase ('foll...
متن کاملDouble-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles
Alopecia areata (AA), a chronic, relapsing, hair-loss disorder, is considered to be a T cell-mediated autoimmune disease. It affects approximately 1.7% of the population, but its precise pathogenesis remains to be elucidated. Despite the recent attention focused on the roles of inflammasomes in the pathogenesis of autoinflammatory diseases, little is known about inflammasome activation in AA. T...
متن کاملCD10 and CD34 in fetal and adult human hair follicles: dynamic changes in their immunohistochemical expression during embryogenesis and hair cycling.
BACKGROUND CD10 and CD34 have been detected in both epithelial and mesenchymal components of anagen human hair follicles. OBJECTIVES To analyse the expression of CD10 and CD34 in human hair follicle development as well as in different phases of the hair cycle. METHODS Fetal and adult hair follicles at different stages of the hair cycle were examined by immunohistochemistry for CD10 and CD34...
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ژورنال
عنوان ژورنال: Nihon Chikusan Gakkaiho
سال: 1991
ISSN: 1346-907X,1880-8255
DOI: 10.2508/chikusan.62.714